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tecovirimat will improve the amount or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Watch. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Keep an eye on for adverse results if coadministered with delicate substrates of these enzymes.ceritinib will increase the amount or outcome of diazepam by affecting hep